10 / July / 2026 Cancer treatments advance, but clinical trials lack diversity Most drugs are tested on populations from wealthy countries—expanding participation to other regions could make therapies more effective for different patient profiles By Gabriela Monteiro
17 / June / 2026 Pulmonary fibrosis: AI-developed drug shows promising early results Clinical trial indicates improvement in a measure of lung function, but safety, efficacy, and use with other populations still need to be confirmed By Daniel Dieb
27 / May / 2026 Lack of ongoing funding jeopardizes the careers of physician-scientists in Brazil Reliance on short-term and uncertain grants undermines the ability of professionals with dual roles to maintain stability and sustain scientific output By Editorial staff
08 / April / 2026 “Without suitable comparison between groups, there is no way of proving the efficacy of a new drug” Cardiologist and researcher at Einstein Hospital Israelita explains the role of randomized clinical trials and the risks of social pressure on clinical research By Moura Leite Netto
12 / March / 2026 Clinical research from the inside: science, careers, and impact on health A hybrid field within healthcare, clinical research presents challenges for which ethics, regulation, and protocols are essential to transforming science into evidence and ensuring patient safety By Patricia Monteiro Quintino
19 / January / 2026 Medical career: planning transitions between clinical practice, research, and industry Drawing on her experience in endocrinology, clinical research, and pharmacovigilance, Sonia Mansoldo Dainesi advises physicians considering career transitions. By Gabriela Monteiro
15 / May / 2025 Otavio Berwanger: “We need to increase the efficiency of randomized clinical trials” Executive director of the George Institute for Global Health UK and chair in Clinical Trials at Imperial College London advocates for more efficient, innovative, and representative clinical trials based on pragmatic designs, digital technology, AI applications, routinely collected data, and patient and public involvement participation By Gilberto Stam
29 / January / 2025 AI could increase accuracy in clinical trials Study reveals that GPT-4 models outperform experts at selecting patients with heart failure, optimizing inclusion in clinical trials, and reducing operational costs By Moura Leite Netto
14 / January / 2025 To reduce costs and increase diversity in clinical studies A US regulatory agency advocates analyzing treatment efficacy by combining observational studies with targeted data collection By Editorial staff
19 / December / 2024 Fighting Alzheimer’s with science and empathy Brazilian biologist is leading research that seeks to develop a simple, less invasive method for diagnosing the disease that affects her mother By Letícia Naísa
